Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 PH-797804 0.6
uM
 2
IL-8
 141.0 40
RA2708 JNK-IN-8 3.0
uM
 2
IL-8
 170.0 60
RA2708 PH-797804 0.6
uM
 2
IL-8
 240.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 83.0 74
RA2159 IKK16 2.0
uM
 2
IL-8
 105.5 72
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 138.0 64
N2645 IKK16 2.0
uM
 2
IL-8
 57.5 62
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-8
 282.0 52
RA2708 IKK16 2.0
uM
 2
IL-8
 90.0 75
RA2159 Tofacitinib 0.3
uM
 2
IL-8
 95.0 63
RA2159 2
IL-8
 144.0 55
N2645 Tofacitinib 0.3
uM
 2
IL-8
 180.5 50
N2645 2
IL-8
 195.0 52
RA2708 Tofacitinib 0.3
uM
 2
IL-8
 276.5 70
RA2708 2
IL-8
 294.5 56
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 198.0 53
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 4112.5 66
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 1582.0 62
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 3194.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-8
 414.0 77
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-8
 7356.5 60
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-8
 12294.0 48
RA2159 TNF-a 100
ng/mL
 2
IL-8
 11947.0 59
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-8
 11843.0 37
N2645 TNF-a 100
ng/mL
 2
IL-8
 12815.5 88