Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset - HMS LINCS Database

Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	Protein Stimulus	Other Stimulus	Stimulus Concentration	Stimulus Conc Unit	ExpPlate	Measured Protein	Measured Protein MFI (a.u.)	Bead Count
N2586	5z-7-oxozeaenol	0.6	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	43.5	62
N2586	IKK16	2.0	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	56.0	63
RA1869	Tofacitinib	0.3	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	70.5	74
RA1869					Poly(I:C)	2	ug/mL	3	FGF Basic	82.0	63
N2759	Tofacitinib	0.3	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	97.0	72
N2759					Poly(I:C)	2	ug/mL	3	FGF Basic	91.0	57
RA1931	Tofacitinib	0.3	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	75.0	69
RA1931					Poly(I:C)	2	ug/mL	3	FGF Basic	92.5	70
N2586	Tofacitinib	0.3	uM		Poly(I:C)	2	ug/mL	3	FGF Basic	110.0	59
N2586					Poly(I:C)	2	ug/mL	3	FGF Basic	103.0	59
RA1869	5z-7-oxozeaenol	0.6	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	37.0	98
RA1869	IKK16	2.0	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	46.0	77
N2759	5z-7-oxozeaenol	0.6	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	37.5	76
N2759	IKK16	2.0	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	62.5	64
RA1931	5z-7-oxozeaenol	0.6	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	42.5	80
RA1931	IKK16	2.0	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	46.0	71
N2586	5z-7-oxozeaenol	0.6	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	42.5	100
N2586	IKK16	2.0	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	61.0	62
RA1869	Tofacitinib	0.3	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	91.0	64
RA1869				IL-1 alpha		100	ng/mL	3	FGF Basic	100.0	67
N2759	Tofacitinib	0.3	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	105.5	76
N2759				IL-1 alpha		100	ng/mL	3	FGF Basic	111.0	67
RA1931	Tofacitinib	0.3	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	104.0	63
RA1931				IL-1 alpha		100	ng/mL	3	FGF Basic	98.0	76
N2586	Tofacitinib	0.3	uM	IL-1 alpha		100	ng/mL	3	FGF Basic	107.0	65