Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 TNF-a 100
ng/mL
 1
IL-4
 91.0 45
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-4
 113.0 44
N2586 TNF-a 100
ng/mL
 1
IL-4
 96.5 54
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 16.0 54
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 21.5 68
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 16.0 57
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 27.0 53
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 19.0 42
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 25.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 22.0 49
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 29.0 40
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 72.0 47
RA1869 IL-1 alpha 100
ng/mL
 1
IL-4
 77.0 47
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 80.5 32
N2759 IL-1 alpha 100
ng/mL
 1
IL-4
 72.0 55
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 61.0 36
RA1931 IL-1 alpha 100
ng/mL
 1
IL-4
 66.0 53
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 81.0 39
N2586 IL-1 alpha 100
ng/mL
 1
IL-4
 93.0 51
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 16.0 70
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 15.0 67
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 18.0 65
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 20.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 18.0 46
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 23.0 73