Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 432.0 63
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 399.5 96
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 286.5 88
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 390.0 85
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 398.0 88
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 412.0 95
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-1B
 360.5 84
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-1B
 396.0 91
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 419.5 78
RA1869 TNF-a 100
ng/mL
 3
IL-1B
 457.5 84
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 402.0 85
N2759 TNF-a 100
ng/mL
 3
IL-1B
 406.0 75
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 429.0 66
RA1931 TNF-a 100
ng/mL
 3
IL-1B
 439.5 80
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-1B
 450.0 95
N2586 TNF-a 100
ng/mL
 3
IL-1B
 448.0 79
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 14.0 52
RA1869 IKK16 2.0
uM
 3
IL-1B
 13.0 99
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 14.0 87
N2759 IKK16 2.0
uM
 3
IL-1B
 11.0 82
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 14.0 82
RA1931 IKK16 2.0
uM
 3
IL-1B
 15.0 95
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-1B
 15.0 89
N2586 IKK16 2.0
uM
 3
IL-1B
 14.0 86
RA1869 Tofacitinib 0.3
uM
 3
IL-1B
 13.0 79