Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 PH-797804 0.6
uM
 3
MMP-3
 124.0 74
N2586 JNK-IN-8 3.0
uM
 3
MMP-3
 99.0 35
N2586 PH-797804 0.6
uM
 3
MMP-3
 104.0 49
0
MMP-3
 43.0 41
0
MMP-3
 33.0 42
0
MMP-3
 35.0 36
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 63.0 61
RA2159 IKK16 2.0
uM
 4
MMP-3
 74.5 50
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 47.0 51
N2645 IKK16 2.0
uM
 4
MMP-3
 89.0 77
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-3
 137.0 50
RA2708 IKK16 2.0
uM
 4
MMP-3
 131.0 67
RA2159 Tofacitinib 0.3
uM
 4
MMP-3
 59.0 52
RA2159 4
MMP-3
 65.0 50
N2645 Tofacitinib 0.3
uM
 4
MMP-3
 44.0 51
N2645 4
MMP-3
 50.5 50
RA2708 Tofacitinib 0.3
uM
 4
MMP-3
 134.0 53
RA2708 4
MMP-3
 97.0 50
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 58.5 62
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 66.0 50
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 37.5 50
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 42.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 164.0 51
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 240.0 58
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-3
 50.0 65