Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IL-1 alpha 100
ng/mL
 3
MMP-1
 18142.0 63
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 26289.0 55
N2759 IL-1 alpha 100
ng/mL
 3
MMP-1
 27327.0 50
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 9943.5 30
RA1931 IL-1 alpha 100
ng/mL
 3
MMP-1
 15491.0 85
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 25421.0 39
N2586 IL-1 alpha 100
ng/mL
 3
MMP-1
 28707.5 34
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 3895.0 48
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 7699.0 50
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 381.5 36
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 2028.5 54
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 5799.5 62
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 8201.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
MMP-1
 1479.5 44
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
MMP-1
 6356.0 44
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 14762.0 37
RA1869 TNF-a 100
ng/mL
 3
MMP-1
 16955.5 54
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 19203.0 64
N2759 TNF-a 100
ng/mL
 3
MMP-1
 21405.0 41
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 7253.0 52
RA1931 TNF-a 100
ng/mL
 3
MMP-1
 10519.0 59
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
MMP-1
 23185.0 49
N2586 TNF-a 100
ng/mL
 3
MMP-1
 30704.0 50
RA1869 5z-7-oxozeaenol 0.6
uM
 3
MMP-1
 3146.0 50
RA1869 IKK16 2.0
uM
 3
MMP-1
 3112.0 48