Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 2754.0 67
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 3972.5 44
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 562.0 37
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 546.0 50
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 7831.0 41
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 8516.0 71
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 1753.0 49
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 1025.5 48
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 5167.5 44
RA1869 Poly(I:C) 2
ug/mL
 3
MMP-1
 7180.0 35
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 1084.0 45
N2759 Poly(I:C) 2
ug/mL
 3
MMP-1
 1536.5 40
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 11192.5 46
RA1931 Poly(I:C) 2
ug/mL
 3
MMP-1
 7467.5 82
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
MMP-1
 6037.0 47
N2586 Poly(I:C) 2
ug/mL
 3
MMP-1
 3117.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 5178.0 59
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 8231.5 56
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 438.0 47
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 7837.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 9457.5 54
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 7009.0 38
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 1239.0 59
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 4385.0 64
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
MMP-1
 17959.5 50