Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 PH-797804 0.6
uM
 2
SCF
 47.0 49
RA2708 JNK-IN-8 3.0
uM
 2
SCF
 48.0 51
RA2708 PH-797804 0.6
uM
 2
SCF
 42.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 2
SCF
 52.0 64
RA2159 IKK16 2.0
uM
 2
SCF
 55.0 72
N2645 5z-7-oxozeaenol 0.6
uM
 2
SCF
 47.0 78
N2645 IKK16 2.0
uM
 2
SCF
 51.0 81
RA2708 5z-7-oxozeaenol 0.6
uM
 2
SCF
 40.0 63
RA2708 IKK16 2.0
uM
 2
SCF
 38.5 64
RA2159 Tofacitinib 0.3
uM
 2
SCF
 45.0 63
RA2159 2
SCF
 46.0 62
N2645 Tofacitinib 0.3
uM
 2
SCF
 46.5 50
N2645 2
SCF
 41.0 41
RA2708 Tofacitinib 0.3
uM
 2
SCF
 46.0 76
RA2708 2
SCF
 41.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 54.0 67
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 57.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 51.0 67
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 53.0 64
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
SCF
 45.0 64
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
SCF
 45.0 65
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SCF
 57.0 67
RA2159 TNF-a 100
ng/mL
 2
SCF
 62.0 55
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
SCF
 51.0 40
N2645 TNF-a 100
ng/mL
 2
SCF
 50.0 61