Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 2
IL1-a
 387.0 57
RA2708 PH-797804 0.6
uM
 2
IL1-a
 429.0 57
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 568.0 69
RA2159 IKK16 2.0
uM
 2
IL1-a
 437.0 80
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 483.0 68
N2645 IKK16 2.0
uM
 2
IL1-a
 433.0 77
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL1-a
 540.0 57
RA2708 IKK16 2.0
uM
 2
IL1-a
 494.0 56
RA2159 Tofacitinib 0.3
uM
 2
IL1-a
 484.0 83
RA2159 2
IL1-a
 465.5 52
N2645 Tofacitinib 0.3
uM
 2
IL1-a
 328.0 43
N2645 2
IL1-a
 451.0 49
RA2708 Tofacitinib 0.3
uM
 2
IL1-a
 366.0 64
RA2708 2
IL1-a
 475.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 411.0 75
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 383.0 51
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 321.0 59
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 385.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL1-a
 398.0 85
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL1-a
 459.0 66
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 338.0 65
RA2159 TNF-a 100
ng/mL
 2
IL1-a
 297.0 60
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 385.0 47
N2645 TNF-a 100
ng/mL
 2
IL1-a
 301.0 55
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL1-a
 389.0 38