Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 22.5 48
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 23.0 49
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 23.0 51
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 21.5 44
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 22.5 50
RA2159 TNF-a 100
ng/mL
 4
IL18
 15.0 37
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 25.0 45
N2645 TNF-a 100
ng/mL
 4
IL18
 26.0 42
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
IL18
 24.0 47
RA2708 TNF-a 100
ng/mL
 4
IL18
 24.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
 4
IL18
 22.5 30
RA2159 IKK16 2.0
uM
 4
IL18
 22.5 54
N2645 5z-7-oxozeaenol 0.6
uM
 4
IL18
 22.0 51
N2645 IKK16 2.0
uM
 4
IL18
 18.5 60
RA2708 5z-7-oxozeaenol 0.6
uM
 4
IL18
 23.0 44
RA2708 IKK16 2.0
uM
 4
IL18
 20.0 59
RA2159 Tofacitinib 0.3
uM
 4
IL18
 24.0 56
RA2159 4
IL18
 22.0 45
N2645 Tofacitinib 0.3
uM
 4
IL18
 22.0 33
N2645 4
IL18
 20.0 36
RA2708 Tofacitinib 0.3
uM
 4
IL18
 23.0 43
RA2708 4
IL18
 21.0 35
RA2159 4
IL18
 26.5 44
N2645 4
IL18
 22.0 32
RA2708 4
IL18
 23.5 54