Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 23.0 53
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 25.0 43
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 28.0 51
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 23.0 45
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 23.0 59
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 26.5 60
RA2159 Poly(I:C) 2
ug/mL
 4
IL18
 24.0 49
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 26.0 50
N2645 Poly(I:C) 2
ug/mL
 4
IL18
 28.0 41
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL18
 19.5 44
RA2708 Poly(I:C) 2
ug/mL
 4
IL18
 23.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 46.0 53
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 39.0 66
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 39.0 60
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 36.0 46
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 43.0 59
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 45.0 38
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 43.0 47
RA2159 IL-1 alpha 100
ng/mL
 4
IL18
 47.0 59
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 38.5 34
N2645 IL-1 alpha 100
ng/mL
 4
IL18
 36.0 51
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL18
 44.5 36
RA2708 IL-1 alpha 100
ng/mL
 4
IL18
 47.0 47
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
IL18
 25.0 42
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
IL18
 27.0 47