Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 36.5 46
RA1931 TNF-a 100
ng/mL
 3
TNFb
 31.5 54
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
TNFb
 39.5 52
N2586 TNF-a 100
ng/mL
 3
TNFb
 30.5 42
RA1869 5z-7-oxozeaenol 0.6
uM
 3
TNFb
 39.5 56
RA1869 IKK16 2.0
uM
 3
TNFb
 41.0 64
N2759 5z-7-oxozeaenol 0.6
uM
 3
TNFb
 44.0 62
N2759 IKK16 2.0
uM
 3
TNFb
 34.0 82
RA1931 5z-7-oxozeaenol 0.6
uM
 3
TNFb
 34.5 62
RA1931 IKK16 2.0
uM
 3
TNFb
 33.5 50
N2586 5z-7-oxozeaenol 0.6
uM
 3
TNFb
 35.0 59
N2586 IKK16 2.0
uM
 3
TNFb
 30.0 61
RA1869 Tofacitinib 0.3
uM
 3
TNFb
 34.0 53
RA1869 3
TNFb
 33.0 54
N2759 Tofacitinib 0.3
uM
 3
TNFb
 35.5 58
N2759 3
TNFb
 38.0 49
RA1931 Tofacitinib 0.3
uM
 3
TNFb
 36.0 67
RA1931 3
TNFb
 38.5 48
N2586 Tofacitinib 0.3
uM
 3
TNFb
 28.0 55
N2586 3
TNFb
 31.0 47
RA1869 3
TNFb
 39.0 38
N2759 3
TNFb
 34.0 53
RA1931 3
TNFb
 31.0 61
N2586 3
TNFb
 35.5 56
RA1869 JNK-IN-8 3.0
uM
 3
TNFb
 35.0 47