Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 JNK-IN-8 3.0
uM
 2
IL-10
 40.0 79
N2645 PH-797804 0.6
uM
 2
IL-10
 43.0 63
RA2708 JNK-IN-8 3.0
uM
 2
IL-10
 39.0 73
RA2708 PH-797804 0.6
uM
 2
IL-10
 46.5 70
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 40.0 67
RA2159 IKK16 2.0
uM
 2
IL-10
 43.0 51
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 37.0 55
N2645 IKK16 2.0
uM
 2
IL-10
 33.0 53
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 44.0 64
RA2708 IKK16 2.0
uM
 2
IL-10
 39.0 72
RA2159 Tofacitinib 0.3
uM
 2
IL-10
 41.5 80
RA2159 2
IL-10
 51.5 66
N2645 Tofacitinib 0.3
uM
 2
IL-10
 39.0 62
N2645 2
IL-10
 49.0 79
RA2708 Tofacitinib 0.3
uM
 2
IL-10
 42.0 51
RA2708 2
IL-10
 49.0 61
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 47.0 63
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 62.0 78
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 51.0 79
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 62.0 60
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 48.0 74
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 54.5 60
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 69.0 51
RA2159 TNF-a 100
ng/mL
 2
IL-10
 63.0 56
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 56.0 62