Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 31.0 53
N2759 IKK16 2.0
uM
 1
IL-10
 39.0 63
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 39.0 66
RA1931 IKK16 2.0
uM
 1
IL-10
 23.0 72
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-10
 47.5 64
N2586 IKK16 2.0
uM
 1
IL-10
 47.0 57
RA1869 Tofacitinib 0.3
uM
 1
IL-10
 45.0 52
RA1869 1
IL-10
 58.0 46
N2759 Tofacitinib 0.3
uM
 1
IL-10
 44.0 46
N2759 1
IL-10
 51.0 53
RA1931 Tofacitinib 0.3
uM
 1
IL-10
 49.0 54
RA1931 1
IL-10
 41.0 48
N2586 Tofacitinib 0.3
uM
 1
IL-10
 63.0 42
N2586 1
IL-10
 48.5 54
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 57.0 60
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 55.0 74
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 51.0 63
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 31.0 74
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 52.0 78
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 62.0 81
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-10
 54.0 66
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-10
 69.0 67
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 84.0 47
RA1869 TNF-a 100
ng/mL
 1
IL-10
 71.5 62
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-10
 73.5 48