Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 4
IL-12 (p70)
 75.5 56
N2645 Tofacitinib 0.3
uM
 4
IL-12 (p70)
 67.0 49
N2645 4
IL-12 (p70)
 64.5 50
RA2708 Tofacitinib 0.3
uM
 4
IL-12 (p70)
 69.0 51
RA2708 4
IL-12 (p70)
 65.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 71.0 57
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 84.0 54
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 50.5 60
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 50.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 77.5 60
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 66.0 63
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 71.0 57
RA2159 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 83.0 69
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 54.5 44
N2645 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 88.5 48
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 88.0 46
RA2708 Poly(I:C) 2
ug/mL
 4
IL-12 (p70)
 71.5 62
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 63.5 58
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 83.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 62.0 63
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 72.0 52
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 77.0 70
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 79.0 45
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 99.5 56
RA2159 IL-1 alpha 100
ng/mL
 4
IL-12 (p70)
 111.5 54