Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 7284.0 73
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 10228.0 110
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 3630.0 69
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 11810.0 86
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 23056.0 99
RA1869 TNF-a 100
ng/mL
 3
IL-6
 20097.0 77
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 9538.0 85
N2759 TNF-a 100
ng/mL
 3
IL-6
 11418.0 73
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 18891.0 65
RA1931 TNF-a 100
ng/mL
 3
IL-6
 21349.0 69
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 17787.0 60
N2586 TNF-a 100
ng/mL
 3
IL-6
 24057.0 77
RA1869 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 855.0 61
RA1869 IKK16 2.0
uM
 3
IL-6
 780.0 95
N2759 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 1153.0 72
N2759 IKK16 2.0
uM
 3
IL-6
 1282.0 81
RA1931 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 2266.0 85
RA1931 IKK16 2.0
uM
 3
IL-6
 3290.0 93
N2586 5z-7-oxozeaenol 0.6
uM
 3
IL-6
 2633.0 85
N2586 IKK16 2.0
uM
 3
IL-6
 2041.0 73
RA1869 Tofacitinib 0.3
uM
 3
IL-6
 2202.0 78
RA1869 3
IL-6
 1447.0 75
N2759 Tofacitinib 0.3
uM
 3
IL-6
 1175.0 81
N2759 3
IL-6
 1006.5 82
RA1931 Tofacitinib 0.3
uM
 3
IL-6
 3944.5 94