Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Poly(I:C) 2
ug/mL
 3
IL-6
 26185.5 70
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 23625.0 79
RA1931 Poly(I:C) 2
ug/mL
 3
IL-6
 30885.0 79
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
IL-6
 36905.5 70
N2586 Poly(I:C) 2
ug/mL
 3
IL-6
 35767.5 62
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 1103.0 99
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 11294.0 76
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 1158.0 83
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 15888.5 82
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 3354.0 65
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 10013.0 73
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 2591.5 90
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 16294.0 81
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 33628.0 86
RA1869 IL-1 alpha 100
ng/mL
 3
IL-6
 35414.5 68
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 39011.0 63
N2759 IL-1 alpha 100
ng/mL
 3
IL-6
 38533.0 73
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 36689.0 75
RA1931 IL-1 alpha 100
ng/mL
 3
IL-6
 37315.0 86
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
IL-6
 39158.5 78
N2586 IL-1 alpha 100
ng/mL
 3
IL-6
 40558.5 70
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 5516.5 62
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 11205.0 89
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
IL-6
 1120.0 65
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 4576.5 90