Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 2
MMP-2
 138.0 44
RA2159 PH-797804 0.6
uM
 2
MMP-2
 164.0 33
N2645 JNK-IN-8 3.0
uM
 2
MMP-2
 137.0 32
N2645 PH-797804 0.6
uM
 2
MMP-2
 155.0 31
RA2708 JNK-IN-8 3.0
uM
 2
MMP-2
 344.5 34
RA2708 PH-797804 0.6
uM
 2
MMP-2
 301.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 125.0 39
RA2159 IKK16 2.0
uM
 2
MMP-2
 139.5 34
N2645 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 124.5 24
N2645 IKK16 2.0
uM
 2
MMP-2
 112.0 35
RA2708 5z-7-oxozeaenol 0.6
uM
 2
MMP-2
 320.0 25
RA2708 IKK16 2.0
uM
 2
MMP-2
 255.5 34
RA2159 Tofacitinib 0.3
uM
 2
MMP-2
 95.0 37
RA2159 2
MMP-2
 101.5 44
N2645 Tofacitinib 0.3
uM
 2
MMP-2
 108.0 50
N2645 2
MMP-2
 107.0 42
RA2708 Tofacitinib 0.3
uM
 2
MMP-2
 321.0 39
RA2708 2
MMP-2
 247.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 118.0 34
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 130.5 50
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 106.5 38
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 103.0 37
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
MMP-2
 189.0 50
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
MMP-2
 211.0 50
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
MMP-2
 152.5 50