Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 27.0 | 49 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 24.0 | 55 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 15.5 | 24 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 22.0 | 53 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 24.0 | 37 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 23.0 | 28 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 24.5 | 66 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 23.5 | 48 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 19.0 | 41 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-1 | 29.0 | 44 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-1 | 26.0 | 52 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-1 | 19.0 | 41 | |||||
| 0 | MMP-2 | 4.0 | 33 | ||||||||
| 0 | MMP-2 | 6.0 | 25 | ||||||||
| 0 | MMP-2 | 3.0 | 46 | ||||||||
| RA1869 | 1 | MMP-2 | 532.0 | 41 | |||||||
| N2759 | 1 | MMP-2 | 505.0 | 56 | |||||||
| RA1931 | 1 | MMP-2 | 384.0 | 52 | |||||||
| N2586 | 1 | MMP-2 | 623.0 | 39 | |||||||
| RA1869 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 492.5 | 50 | ||||
| RA1869 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 688.0 | 53 | ||||
| N2759 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 390.0 | 51 | ||||
| N2759 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 320.5 | 30 | ||||
| RA1931 | JNK-IN-8 | 3.0 | uM | 1 | MMP-2 | 244.0 | 31 | ||||
| RA1931 | PH-797804 | 0.6 | uM | 1 | MMP-2 | 338.0 | 19 |