Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
 3
MMP-1
 1123.0 22
N2586 PH-797804 0.6
uM
 3
MMP-1
 765.0 49
0
MMP-1
 22.0 50
0
MMP-1
 25.0 41
0
MMP-1
 26.0 42
RA2159 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 245.5 50
RA2159 IKK16 2.0
uM
 4
MMP-1
 216.0 66
N2645 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 118.0 50
N2645 IKK16 2.0
uM
 4
MMP-1
 94.0 74
RA2708 5z-7-oxozeaenol 0.6
uM
 4
MMP-1
 1235.0 63
RA2708 IKK16 2.0
uM
 4
MMP-1
 1582.5 54
RA2159 Tofacitinib 0.3
uM
 4
MMP-1
 270.5 50
RA2159 4
MMP-1
 142.5 56
N2645 Tofacitinib 0.3
uM
 4
MMP-1
 67.0 57
N2645 4
MMP-1
 92.0 57
RA2708 Tofacitinib 0.3
uM
 4
MMP-1
 1411.5 50
RA2708 4
MMP-1
 1215.5 68
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 178.5 74
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 188.0 57
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 61.0 61
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 56.5 66
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 1426.0 67
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 1365.0 74
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
MMP-1
 145.5 70
RA2159 Poly(I:C) 2
ug/mL
 4
MMP-1
 230.0 63