Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 75
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 62
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 23.0 61
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 59
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 67
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 20.5 64
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 17.5 62
RA1869 Poly(I:C) 2
ug/mL
 3
TRAIL
 21.0 62
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 24.0 83
N2759 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 65
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 20.0 70
RA1931 Poly(I:C) 2
ug/mL
 3
TRAIL
 23.0 49
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TRAIL
 22.0 60
N2586 Poly(I:C) 2
ug/mL
 3
TRAIL
 19.0 65
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 39.0 47
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 42.0 78
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.0 97
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 40.5 70
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.0 76
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 40.0 74
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.0 67
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 42.0 67
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 40.0 89
RA1869 IL-1 alpha 100
ng/mL
 3
TRAIL
 43.0 73
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
TRAIL
 45.0 67