Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 TNF-a 100
ng/mL
 1
MMP-2
 950.0 17
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 380.0 30
N2759 TNF-a 100
ng/mL
 1
MMP-2
 379.0 50
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 493.5 26
RA1931 TNF-a 100
ng/mL
 1
MMP-2
 930.0 47
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
MMP-2
 773.0 23
N2586 TNF-a 100
ng/mL
 1
MMP-2
 322.0 9
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 444.0 12
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 705.0 35
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 178.0 39
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 356.0 28
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 334.0 48
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 426.0 11
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 295.5 30
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 243.0 25
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 553.5 60
RA1869 IL-1 alpha 100
ng/mL
 1
MMP-2
 786.0 29
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 293.0 21
N2759 IL-1 alpha 100
ng/mL
 1
MMP-2
 374.0 27
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 661.5 12
RA1931 IL-1 alpha 100
ng/mL
 1
MMP-2
 441.0 37
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-2
 622.0 40
N2586 IL-1 alpha 100
ng/mL
 1
MMP-2
 334.0 16
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-2
 626.0 25
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-2
 902.0 33