Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Poly(I:C) 2
ug/mL
 3
SCF
 38.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 42.0 49
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 42.5 56
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 35.5 78
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 34.5 60
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 48.0 68
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 50.0 71
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 35.5 68
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 37.0 57
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 47.0 56
RA1869 IL-1 alpha 100
ng/mL
 3
SCF
 47.0 55
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 39.5 58
N2759 IL-1 alpha 100
ng/mL
 3
SCF
 42.0 48
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 63.5 56
RA1931 IL-1 alpha 100
ng/mL
 3
SCF
 77.0 54
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
SCF
 45.0 58
N2586 IL-1 alpha 100
ng/mL
 3
SCF
 43.0 49
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 36.0 57
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 37.0 70
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 29.0 53
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 34.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 44.0 69
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 41.5 50
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
SCF
 31.0 58
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
SCF
 34.0 60