Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 854.0 49
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 1606.0 37
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 16852.5 42
RA1869 IL-1 alpha 100
ng/mL
 1
MMP-1
 25102.0 30
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 24292.0 28
N2759 IL-1 alpha 100
ng/mL
 1
MMP-1
 27749.0 49
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 14304.0 16
RA1931 IL-1 alpha 100
ng/mL
 1
MMP-1
 11726.0 33
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MMP-1
 24805.0 53
N2586 IL-1 alpha 100
ng/mL
 1
MMP-1
 25444.5 22
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 3105.5 24
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 3924.5 38
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 731.5 48
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 476.5 32
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 7009.0 32
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 8272.5 26
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 813.0 31
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 1138.5 44
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 4640.0 27
RA1869 Poly(I:C) 2
ug/mL
 1
MMP-1
 5129.0 46
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 2328.5 38
N2759 Poly(I:C) 2
ug/mL
 1
MMP-1
 3666.0 28
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 8736.0 49
RA1931 Poly(I:C) 2
ug/mL
 1
MMP-1
 8167.0 14
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MMP-1
 3407.0 59