Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL3
44.0 53
RA1931 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL3
41.5 38
RA1931 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL3
33.5 56
N2586 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL3
30.0 65
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL3
29.5 58
RA1869 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL3
29.5 38
RA1869 Poly(I:C) 2
ug/mL
3
IL3
38.5 46
N2759 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL3
54.0 43
N2759 Poly(I:C) 2
ug/mL
3
IL3
35.0 51
RA1931 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL3
34.5 28
RA1931 Poly(I:C) 2
ug/mL
3
IL3
30.0 42
N2586 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL3
29.0 45
N2586 Poly(I:C) 2
ug/mL
3
IL3
32.0 33
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL3
73.0 32
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL3
67.0 41
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL3
70.5 62
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL3
79.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL3
70.5 54
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL3
62.5 48
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL3
72.0 44
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL3
63.0 55
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL3
73.0 52
RA1869 IL-1 alpha 100
ng/mL
3
IL3
69.0 56
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL3
72.0 34
N2759 IL-1 alpha 100
ng/mL
3
IL3
63.0 47