Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2759 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | SCGF-b | 432.0 | 67 | |
N2759 | TNF-a | 100 | ng/mL | 1 | SCGF-b | 384.0 | 72 | ||||
RA1931 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | SCGF-b | 235.0 | 61 | |
RA1931 | TNF-a | 100 | ng/mL | 1 | SCGF-b | 290.5 | 78 | ||||
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | SCGF-b | 279.5 | 54 | |
N2586 | TNF-a | 100 | ng/mL | 1 | SCGF-b | 297.0 | 67 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 195.0 | 46 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 195.0 | 66 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 151.0 | 67 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 186.5 | 60 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 155.5 | 58 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 176.0 | 61 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 150.0 | 78 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 155.5 | 66 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 258.0 | 60 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 307.5 | 56 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 231.5 | 82 | |
N2759 | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 199.0 | 63 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 275.0 | 77 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 203.0 | 65 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 247.0 | 38 | |
N2586 | IL-1 alpha | 100 | ng/mL | 1 | SCGF-b | 201.0 | 39 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | SCGF-b | 162.0 | 44 | |
RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | SCGF-b | 178.0 | 53 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | SCGF-b | 140.0 | 57 |