Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
HGF
 24.0 79
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
HGF
 27.0 71
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
HGF
 38.0 62
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
HGF
 37.0 65
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
HGF
 30.0 78
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
HGF
 22.0 61
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
HGF
 29.0 70
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
HGF
 27.0 62
RA1869 TNF-a 100
ng/mL
 1
HGF
 33.0 65
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
HGF
 39.0 42
N2759 TNF-a 100
ng/mL
 1
HGF
 30.5 60
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
HGF
 43.0 51
RA1931 TNF-a 100
ng/mL
 1
HGF
 80.0 54
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
HGF
 39.0 30
N2586 TNF-a 100
ng/mL
 1
HGF
 33.0 50
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 53.0 51
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 48.0 57
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 49.0 74
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 54.0 49
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 65.0 52
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 64.5 54
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 45.5 62
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 45.0 61
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
HGF
 55.0 49
RA1869 IL-1 alpha 100
ng/mL
 1
HGF
 55.5 60