Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 4
TRAIL
 33.5 50
RA2708 Poly(I:C) 2
ug/mL
 4
TRAIL
 35.0 61
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 61.0 66
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 59.0 79
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 55.0 68
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 57.0 69
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 57.5 74
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 51.5 58
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 62.0 59
RA2159 IL-1 alpha 100
ng/mL
 4
TRAIL
 57.0 49
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 59.0 73
N2645 IL-1 alpha 100
ng/mL
 4
TRAIL
 51.0 66
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
TRAIL
 55.0 53
RA2708 IL-1 alpha 100
ng/mL
 4
TRAIL
 51.5 46
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TRAIL
 30.0 67
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TRAIL
 29.0 88
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TRAIL
 29.0 68
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TRAIL
 25.5 76
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TRAIL
 32.0 81
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TRAIL
 30.0 61
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TRAIL
 30.0 77
RA2159 TNF-a 100
ng/mL
 4
TRAIL
 31.0 71
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TRAIL
 28.5 72
N2645 TNF-a 100
ng/mL
 4
TRAIL
 30.0 77
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TRAIL
 32.5 60