Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 142.0 47
N2586 IL-1 alpha 100
ng/mL
 3
b-NGF
 169.0 59
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
b-NGF
 40.5 50
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
b-NGF
 38.5 44
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
b-NGF
 24.0 62
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
b-NGF
 22.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
b-NGF
 124.5 64
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
b-NGF
 107.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 3
b-NGF
 37.0 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
b-NGF
 40.5 44
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 71.0 49
RA1869 TNF-a 100
ng/mL
 3
b-NGF
 63.0 60
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 69.0 64
N2759 TNF-a 100
ng/mL
 3
b-NGF
 71.0 46
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 159.5 58
RA1931 TNF-a 100
ng/mL
 3
b-NGF
 216.0 60
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
b-NGF
 97.0 57
N2586 TNF-a 100
ng/mL
 3
b-NGF
 142.0 56
RA1869 5z-7-oxozeaenol 0.6
uM
 3
b-NGF
 32.0 57
RA1869 IKK16 2.0
uM
 3
b-NGF
 27.0 49
N2759 5z-7-oxozeaenol 0.6
uM
 3
b-NGF
 24.0 64
N2759 IKK16 2.0
uM
 3
b-NGF
 22.0 54
RA1931 5z-7-oxozeaenol 0.6
uM
 3
b-NGF
 83.0 44
RA1931 IKK16 2.0
uM
 3
b-NGF
 72.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 3
b-NGF
 36.0 53