Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 116.0 54
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 47.5 54
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 38.0 71
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 64.0 53
RA1869 Poly(I:C) 2
ug/mL
 3
b-NGF
 95.0 41
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 52.0 43
N2759 Poly(I:C) 2
ug/mL
 3
b-NGF
 62.0 67
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 154.5 48
RA1931 Poly(I:C) 2
ug/mL
 3
b-NGF
 165.5 50
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
b-NGF
 92.0 49
N2586 Poly(I:C) 2
ug/mL
 3
b-NGF
 94.0 44
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 59.0 59
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 53.5 66
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 42.0 55
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 41.0 59
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 111.0 53
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 113.0 60
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 42.0 49
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 48.5 64
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 88.0 48
RA1869 IL-1 alpha 100
ng/mL
 3
b-NGF
 103.5 50
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 107.0 48
N2759 IL-1 alpha 100
ng/mL
 3
b-NGF
 127.0 51
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 3
b-NGF
 285.0 49
RA1931 IL-1 alpha 100
ng/mL
 3
b-NGF
 353.0 51