Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
TNFb
37.0 52
RA1931 TNF-a 100
ng/mL
3
TNFb
37.0 43
N2586 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
3
TNFb
31.0 53
N2586 TNF-a 100
ng/mL
3
TNFb
33.5 70
RA1869 5z-7-oxozeaenol 0.6
uM
3
TNFb
35.5 40
RA1869 IKK16 2.0
uM
3
TNFb
38.0 49
N2759 5z-7-oxozeaenol 0.6
uM
3
TNFb
32.5 54
N2759 IKK16 2.0
uM
3
TNFb
30.0 51
RA1931 5z-7-oxozeaenol 0.6
uM
3
TNFb
33.0 59
RA1931 IKK16 2.0
uM
3
TNFb
32.0 60
N2586 5z-7-oxozeaenol 0.6
uM
3
TNFb
26.5 50
N2586 IKK16 2.0
uM
3
TNFb
35.0 49
RA1869 Tofacitinib 0.3
uM
3
TNFb
30.0 54
RA1869 3
TNFb
34.0 39
N2759 Tofacitinib 0.3
uM
3
TNFb
36.5 52
N2759 3
TNFb
31.0 51
RA1931 Tofacitinib 0.3
uM
3
TNFb
34.0 41
RA1931 3
TNFb
35.0 42
N2586 Tofacitinib 0.3
uM
3
TNFb
31.0 58
N2586 3
TNFb
28.0 57
RA1869 3
TNFb
29.5 30
N2759 3
TNFb
27.5 52
RA1931 3
TNFb
34.0 47
N2586 3
TNFb
27.0 61
RA1869 JNK-IN-8 3.0
uM
3
TNFb
30.5 42