Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 Tofacitinib 0.3
uM
 3
TNFb
 34.5 46
N2759 3
TNFb
 28.5 60
RA1931 Tofacitinib 0.3
uM
 3
TNFb
 30.0 42
RA1931 3
TNFb
 36.5 50
N2586 Tofacitinib 0.3
uM
 3
TNFb
 32.5 48
N2586 3
TNFb
 31.0 41
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 34.0 41
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 28.0 71
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 32.0 72
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 36.0 60
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 31.5 42
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 34.0 43
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 32.5 68
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 31.5 56
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 32.0 36
RA1869 Poly(I:C) 2
ug/mL
 3
TNFb
 28.0 46
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 34.5 42
N2759 Poly(I:C) 2
ug/mL
 3
TNFb
 36.0 48
RA1931 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 30.5 34
RA1931 Poly(I:C) 2
ug/mL
 3
TNFb
 30.0 52
N2586 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 3
TNFb
 32.0 55
N2586 Poly(I:C) 2
ug/mL
 3
TNFb
 25.0 52
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 75.5 48
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 85.0 65
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 3
TNFb
 92.5 60