Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
LIF
 44.5 48
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
LIF
 55.0 45
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
LIF
 45.0 44
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
LIF
 65.0 39
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 79.0 45
RA1869 TNF-a 100
ng/mL
 1
LIF
 80.0 46
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 69.0 38
N2759 TNF-a 100
ng/mL
 1
LIF
 66.0 59
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 65.0 43
RA1931 TNF-a 100
ng/mL
 1
LIF
 75.0 51
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
LIF
 66.0 34
N2586 TNF-a 100
ng/mL
 1
LIF
 75.0 39
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 116.0 33
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 131.0 39
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 124.0 43
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 132.0 33
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 127.5 46
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 129.0 40
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 122.5 46
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 130.0 49
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 217.0 36
RA1869 IL-1 alpha 100
ng/mL
 1
LIF
 225.0 48
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 192.0 43
N2759 IL-1 alpha 100
ng/mL
 1
LIF
 211.0 46
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
LIF
 283.0 35