Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 53.0 67
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 197.0 64
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 221.5 66
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 55.0 66
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 46.0 71
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 118.0 51
RA2159 IL-1 alpha 100
ng/mL
 4
b-NGF
 103.0 47
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 475.0 65
N2645 IL-1 alpha 100
ng/mL
 4
b-NGF
 434.0 72
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
b-NGF
 93.0 58
RA2708 IL-1 alpha 100
ng/mL
 4
b-NGF
 71.0 43
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 53.0 47
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 49.0 60
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 161.0 53
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 211.5 72
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
b-NGF
 45.5 68
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
b-NGF
 28.0 70
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 109.0 57
RA2159 TNF-a 100
ng/mL
 4
b-NGF
 103.5 58
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 346.0 60
N2645 TNF-a 100
ng/mL
 4
b-NGF
 342.0 81
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
b-NGF
 66.5 50
RA2708 TNF-a 100
ng/mL
 4
b-NGF
 73.0 52
RA2159 5z-7-oxozeaenol 0.6
uM
 4
b-NGF
 48.0 27
RA2159 IKK16 2.0
uM
 4
b-NGF
 30.0 57