Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 24.0 97
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 27.0 84
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 26.0 69
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 33.0 73
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 26.0 68
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 27.5 78
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 153.0 65
RA1869 IL-1 alpha 100
ng/mL
 1
MCP3
 272.5 84
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 96.5 82
N2759 IL-1 alpha 100
ng/mL
 1
MCP3
 96.0 78
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 340.0 67
RA1931 IL-1 alpha 100
ng/mL
 1
MCP3
 420.0 85
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
MCP3
 187.5 46
N2586 IL-1 alpha 100
ng/mL
 1
MCP3
 175.0 32
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 20.0 49
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 20.0 64
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 18.0 72
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 17.0 71
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 15.0 97
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 18.5 72
N2586 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 19.0 60
N2586 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 20.0 71
RA1869 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 49.0 57
RA1869 Poly(I:C) 2
ug/mL
 1
MCP3
 86.5 44
N2759 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 1
MCP3
 21.5 60