Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 30.0 63
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 4
TNFb
 34.0 62
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 4
TNFb
 32.0 61
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TNFb
 39.0 67
RA2159 TNF-a 100
ng/mL
 4
TNFb
 36.0 53
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TNFb
 29.0 55
N2645 TNF-a 100
ng/mL
 4
TNFb
 28.5 56
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 4
TNFb
 29.0 41
RA2708 TNF-a 100
ng/mL
 4
TNFb
 28.5 38
RA2159 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 37.0 49
RA2159 IKK16 2.0
uM
 4
TNFb
 28.5 52
N2645 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 32.0 66
N2645 IKK16 2.0
uM
 4
TNFb
 30.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 4
TNFb
 29.0 51
RA2708 IKK16 2.0
uM
 4
TNFb
 31.0 57
RA2159 Tofacitinib 0.3
uM
 4
TNFb
 29.0 42
RA2159 4
TNFb
 32.5 34
N2645 Tofacitinib 0.3
uM
 4
TNFb
 31.0 55
N2645 4
TNFb
 29.5 38
RA2708 Tofacitinib 0.3
uM
 4
TNFb
 30.0 35
RA2708 4
TNFb
 30.0 43
RA2159 4
TNFb
 37.5 16
N2645 4
TNFb
 31.0 46
RA2708 4
TNFb
 32.0 52
RA2159 JNK-IN-8 3.0
uM
 4
TNFb
 34.0 45