Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 43.5 66
RA2159 PH-797804 0.6
uM
 2
IL-12 (p70)
 47.0 48
N2645 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 33.0 59
N2645 PH-797804 0.6
uM
 2
IL-12 (p70)
 29.0 62
RA2708 JNK-IN-8 3.0
uM
 2
IL-12 (p70)
 43.5 48
RA2708 PH-797804 0.6
uM
 2
IL-12 (p70)
 39.0 45
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 42.0 66
RA2159 IKK16 2.0
uM
 2
IL-12 (p70)
 39.0 60
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 31.0 64
N2645 IKK16 2.0
uM
 2
IL-12 (p70)
 34.0 71
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-12 (p70)
 39.0 63
RA2708 IKK16 2.0
uM
 2
IL-12 (p70)
 44.0 64
RA2159 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 47.5 70
RA2159 2
IL-12 (p70)
 56.0 67
N2645 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 28.5 80
N2645 2
IL-12 (p70)
 33.0 61
RA2708 Tofacitinib 0.3
uM
 2
IL-12 (p70)
 46.5 56
RA2708 2
IL-12 (p70)
 43.5 64
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 46.0 50
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 59.0 46
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 34.0 45
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 40.0 58
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 45.0 61
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 58.0 43
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-12 (p70)
 55.0 52