Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 64.0 | 47 | |
| N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 49.0 | 49 | |
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 71.0 | 53 | |
| RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 93.5 | 46 | |
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 57.0 | 45 | |
| N2586 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 70.0 | 61 | |
| RA1869 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 103.5 | 42 | |
| RA1869 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 134.0 | 34 | ||||
| N2759 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 78.0 | 46 | |
| N2759 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 87.0 | 41 | ||||
| RA1931 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 104.0 | 50 | |
| RA1931 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 111.0 | 57 | ||||
| N2586 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 86.0 | 49 | |
| N2586 | Poly(I:C) | 2 | ug/mL | 1 | IL-12 (p70) | 90.0 | 54 | ||||
| RA1869 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 64.0 | 66 | ||||
| RA1869 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 88.5 | 50 | ||||
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 62.5 | 66 | ||||
| N2759 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 66.0 | 58 | ||||
| RA1931 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 64.0 | 54 | ||||
| RA1931 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 81.0 | 51 | ||||
| N2586 | 5z-7-oxozeaenol | 0.6 | uM | 1 | IL-12 (p70) | 55.0 | 55 | ||||
| N2586 | IKK16 | 2.0 | uM | 1 | IL-12 (p70) | 70.0 | 59 | ||||
| RA1869 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 93.5 | 48 | ||||
| RA1869 | 1 | IL-12 (p70) | 82.0 | 60 | |||||||
| N2759 | Tofacitinib | 0.3 | uM | 1 | IL-12 (p70) | 57.0 | 40 |