Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 JNK-IN-8 3.0
uM
3
IL-7
13.0 61
N2586 PH-797804 0.6
uM
3
IL-7
13.0 37
0
IL-7
9.0 34
0
IL-7
8.5 26
0
IL-7
10.0 31
RA2159 5z-7-oxozeaenol 0.6
uM
4
IL-7
61.0 38
RA2159 IKK16 2.0
uM
4
IL-7
78.5 60
N2645 5z-7-oxozeaenol 0.6
uM
4
IL-7
13.0 45
N2645 IKK16 2.0
uM
4
IL-7
20.0 41
RA2708 5z-7-oxozeaenol 0.6
uM
4
IL-7
19.0 33
RA2708 IKK16 2.0
uM
4
IL-7
19.5 34
RA2159 Tofacitinib 0.3
uM
4
IL-7
61.0 39
RA2159 4
IL-7
57.5 36
N2645 Tofacitinib 0.3
uM
4
IL-7
8.0 36
N2645 4
IL-7
12.0 32
RA2708 Tofacitinib 0.3
uM
4
IL-7
16.5 20
RA2708 4
IL-7
13.5 26
RA2159 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-7
67.0 29
RA2159 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
IL-7
107.5 30
N2645 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-7
11.0 34
N2645 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
IL-7
14.5 36
RA2708 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
4
IL-7
19.5 34
RA2708 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
4
IL-7
21.5 40
RA2159 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
4
IL-7
70.0 27
RA2159 Poly(I:C) 2
ug/mL
4
IL-7
85.0 19