Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2645 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-7 | 15.0 | 40 | |
N2645 | IL-1 alpha | 100 | ng/mL | 2 | IL-7 | 13.0 | 64 | ||||
RA2708 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 2 | IL-7 | 18.5 | 50 | |
RA2708 | IL-1 alpha | 100 | ng/mL | 2 | IL-7 | 18.0 | 46 | ||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 71.0 | 66 | |
RA2159 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 78.0 | 58 | |
N2645 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 12.0 | 66 | |
N2645 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 10.0 | 63 | |
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 15.0 | 59 | |
RA2708 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 17.0 | 50 | |
RA2159 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 65.0 | 76 | |
RA2159 | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 74.5 | 72 | ||||
N2645 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 11.0 | 48 | |
N2645 | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 11.0 | 61 | ||||
RA2708 | Tofacitinib | 0.3 | uM | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 16.5 | 42 | |
RA2708 | Poly(I:C) | 2 | ug/mL | 2 | IL-7 | 17.5 | 56 | ||||
RA2159 | 5z-7-oxozeaenol | 0.6 | uM | 2 | IL-7 | 65.0 | 63 | ||||
RA2159 | IKK16 | 2.0 | uM | 2 | IL-7 | 70.0 | 67 | ||||
N2645 | 5z-7-oxozeaenol | 0.6 | uM | 2 | IL-7 | 12.0 | 45 | ||||
N2645 | IKK16 | 2.0 | uM | 2 | IL-7 | 12.5 | 58 | ||||
RA2708 | 5z-7-oxozeaenol | 0.6 | uM | 2 | IL-7 | 14.0 | 53 | ||||
RA2708 | IKK16 | 2.0 | uM | 2 | IL-7 | 18.0 | 61 | ||||
RA2159 | Tofacitinib | 0.3 | uM | 2 | IL-7 | 76.0 | 61 | ||||
RA2159 | 2 | IL-7 | 81.0 | 51 | |||||||
N2645 | Tofacitinib | 0.3 | uM | 2 | IL-7 | 14.0 | 59 |