Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2159 2
IL-7
 78.0 75
N2645 Tofacitinib 0.3
uM
 2
IL-7
 11.0 75
N2645 2
IL-7
 13.0 61
RA2708 Tofacitinib 0.3
uM
 2
IL-7
 16.0 60
RA2708 2
IL-7
 12.0 58
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-7
 42.0 56
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-7
 55.5 54
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-7
 11.0 48
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-7
 15.0 65
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-7
 14.0 52
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-7
 17.0 44
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-7
 56.0 69
RA2159 TNF-a 100
ng/mL
 2
IL-7
 61.5 52
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-7
 17.5 54
N2645 TNF-a 100
ng/mL
 2
IL-7
 11.5 56
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-7
 19.0 65
RA2708 TNF-a 100
ng/mL
 2
IL-7
 19.0 41
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 64.0 70
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 74.5 52
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 12.0 69
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 13.0 48
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 13.0 51
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 16.0 61
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-7
 63.5 64
RA2159 IL-1 alpha 100
ng/mL
 2
IL-7
 61.5 50