Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 TNF-a 100
ng/mL
 2
IL-10
 52.5 52
RA2708 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 51.5 54
RA2708 TNF-a 100
ng/mL
 2
IL-10
 51.5 36
RA2159 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 32.0 59
RA2159 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 41.0 58
N2645 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 32.5 70
N2645 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 40.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 36.0 56
RA2708 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 46.5 50
RA2159 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 51.0 73
RA2159 IL-1 alpha 100
ng/mL
 2
IL-10
 49.0 71
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 45.5 58
N2645 IL-1 alpha 100
ng/mL
 2
IL-10
 48.0 53
RA2708 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 2
IL-10
 48.0 47
RA2708 IL-1 alpha 100
ng/mL
 2
IL-10
 50.0 46
RA2159 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 35.0 67
RA2159 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 41.0 45
N2645 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 35.5 64
N2645 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 42.0 61
RA2708 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 40.5 64
RA2708 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 46.0 60
RA2159 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 42.5 74
RA2159 Poly(I:C) 2
ug/mL
 2
IL-10
 56.5 60
N2645 Tofacitinib 0.3
uM
 Poly(I:C) 2
ug/mL
 2
IL-10
 35.0 39
N2645 Poly(I:C) 2
ug/mL
 2
IL-10
 37.0 42