Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2645 JNK-IN-8 3.0
uM
 2
IL-10
 40.0 72
N2645 PH-797804 0.6
uM
 2
IL-10
 41.0 51
RA2708 JNK-IN-8 3.0
uM
 2
IL-10
 40.0 60
RA2708 PH-797804 0.6
uM
 2
IL-10
 39.0 55
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 40.5 60
RA2159 IKK16 2.0
uM
 2
IL-10
 37.5 64
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 33.0 63
N2645 IKK16 2.0
uM
 2
IL-10
 34.5 64
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-10
 43.5 50
RA2708 IKK16 2.0
uM
 2
IL-10
 40.0 74
RA2159 Tofacitinib 0.3
uM
 2
IL-10
 40.5 72
RA2159 2
IL-10
 44.0 75
N2645 Tofacitinib 0.3
uM
 2
IL-10
 39.0 69
N2645 2
IL-10
 39.0 88
RA2708 Tofacitinib 0.3
uM
 2
IL-10
 40.5 64
RA2708 2
IL-10
 43.0 64
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 44.0 53
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 56.0 44
N2645 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 40.0 73
N2645 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 51.0 67
RA2708 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-10
 50.0 69
RA2708 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-10
 54.0 55
RA2159 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 52.0 64
RA2159 TNF-a 100
ng/mL
 2
IL-10
 59.0 57
N2645 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 2
IL-10
 38.5 58