Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 TNF-a 100
ng/mL
 1
IL-4
 133.0 61
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-4
 111.5 60
N2586 TNF-a 100
ng/mL
 1
IL-4
 113.0 63
RA1869 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 19.0 65
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 24.0 47
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 18.0 53
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 21.0 67
RA1931 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 20.0 55
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 27.5 64
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 21.5 50
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 21.5 44
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 76.0 69
RA1869 IL-1 alpha 100
ng/mL
 1
IL-4
 85.0 37
N2759 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 67.0 63
N2759 IL-1 alpha 100
ng/mL
 1
IL-4
 73.5 48
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 71.0 55
RA1931 IL-1 alpha 100
ng/mL
 1
IL-4
 80.0 54
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
IL-4
 86.5 36
N2586 IL-1 alpha 100
ng/mL
 1
IL-4
 84.0 39
RA1869 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 22.0 45
RA1869 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 22.0 56
N2759 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 19.0 48
N2759 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 13.5 52
RA1931 5z-7-oxozeaenol 0.6
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 21.0 60
RA1931 IKK16 2.0
uM
 Poly(I:C) 2
ug/mL
 1
IL-4
 22.0 55