Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
 1
IL-4
 18.0 67
RA1931 IKK16 2.0
uM
 1
IL-4
 18.5 54
N2586 5z-7-oxozeaenol 0.6
uM
 1
IL-4
 18.0 77
N2586 IKK16 2.0
uM
 1
IL-4
 18.0 55
RA1869 Tofacitinib 0.3
uM
 1
IL-4
 17.0 57
RA1869 1
IL-4
 18.0 64
N2759 Tofacitinib 0.3
uM
 1
IL-4
 18.0 81
N2759 1
IL-4
 18.0 59
RA1931 Tofacitinib 0.3
uM
 1
IL-4
 19.5 48
RA1931 1
IL-4
 20.0 58
N2586 Tofacitinib 0.3
uM
 1
IL-4
 20.0 71
N2586 1
IL-4
 19.0 47
RA1869 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-4
 89.5 48
RA1869 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-4
 92.0 54
N2759 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-4
 95.0 64
N2759 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-4
 85.0 55
RA1931 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-4
 85.0 53
RA1931 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-4
 99.0 51
N2586 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 1
IL-4
 84.5 62
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 1
IL-4
 84.5 56
RA1869 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-4
 122.0 73
RA1869 TNF-a 100
ng/mL
 1
IL-4
 120.0 67
N2759 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-4
 80.5 70
N2759 TNF-a 100
ng/mL
 1
IL-4
 111.5 60
RA1931 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 1
IL-4
 131.0 73