Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA1931 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-13
16.0 51
RA1931 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-13
18.0 70
N2586 5z-7-oxozeaenol 0.6
uM
Poly(I:C) 2
ug/mL
3
IL-13
15.0 74
N2586 IKK16 2.0
uM
Poly(I:C) 2
ug/mL
3
IL-13
15.0 91
RA1869 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-13
23.0 55
RA1869 Poly(I:C) 2
ug/mL
3
IL-13
21.0 70
N2759 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-13
18.0 65
N2759 Poly(I:C) 2
ug/mL
3
IL-13
18.0 73
RA1931 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-13
18.0 67
RA1931 Poly(I:C) 2
ug/mL
3
IL-13
19.0 44
N2586 Tofacitinib 0.3
uM
Poly(I:C) 2
ug/mL
3
IL-13
18.5 80
N2586 Poly(I:C) 2
ug/mL
3
IL-13
19.0 47
RA1869 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-13
15.0 53
RA1869 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-13
21.0 57
N2759 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-13
14.0 63
N2759 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-13
15.0 64
RA1931 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-13
16.0 85
RA1931 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-13
18.0 70
N2586 5z-7-oxozeaenol 0.6
uM
IL-1 alpha 100
ng/mL
3
IL-13
12.0 54
N2586 IKK16 2.0
uM
IL-1 alpha 100
ng/mL
3
IL-13
14.0 61
RA1869 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-13
21.0 67
RA1869 IL-1 alpha 100
ng/mL
3
IL-13
24.0 81
N2759 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-13
18.0 75
N2759 IL-1 alpha 100
ng/mL
3
IL-13
20.0 68
RA1931 Tofacitinib 0.3
uM
IL-1 alpha 100
ng/mL
3
IL-13
21.0 47