Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
---|---|---|---|---|---|---|---|---|---|---|---|
N2586 | Tofacitinib | 0.3 | uM | TNF-a | 100 | ng/mL | 1 | IP-10 | 847.0 | 42 | |
N2586 | TNF-a | 100 | ng/mL | 1 | IP-10 | 2347.5 | 56 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 14.0 | 51 | |
RA1869 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 15.0 | 40 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 14.0 | 46 | |
N2759 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 14.0 | 50 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 12.0 | 71 | |
RA1931 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 20.0 | 33 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 16.0 | 34 | |
N2586 | IKK16 | 2.0 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 16.5 | 62 | |
RA1869 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 165.0 | 64 | |
RA1869 | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 615.0 | 41 | ||||
N2759 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 352.0 | 48 | |
N2759 | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 440.0 | 45 | ||||
RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 280.0 | 50 | |
RA1931 | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 518.0 | 45 | ||||
N2586 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 249.5 | 36 | |
N2586 | IL-1 alpha | 100 | ng/mL | 1 | IP-10 | 363.0 | 39 | ||||
RA1869 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 16.0 | 35 | |
RA1869 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 18.0 | 45 | |
N2759 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 48.0 | 63 | |
N2759 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 61.0 | 56 | |
RA1931 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 126.0 | 43 | |
RA1931 | IKK16 | 2.0 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 141.5 | 38 | |
N2586 | 5z-7-oxozeaenol | 0.6 | uM | Poly(I:C) | 2 | ug/mL | 1 | IP-10 | 14.0 | 45 |