Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 IL-1 alpha 100
ng/mL
4
IL-8
12803.0 39
RA2159 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
4
IL-8
335.5 34
RA2159 IKK16 2.0
uM
TNF-a 100
ng/mL
4
IL-8
7515.0 36
N2645 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
4
IL-8
728.5 34
N2645 IKK16 2.0
uM
TNF-a 100
ng/mL
4
IL-8
1418.0 38
RA2708 5z-7-oxozeaenol 0.6
uM
TNF-a 100
ng/mL
4
IL-8
647.0 31
RA2708 IKK16 2.0
uM
TNF-a 100
ng/mL
4
IL-8
9045.0 28
RA2159 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
4
IL-8
11772.5 36
RA2159 TNF-a 100
ng/mL
4
IL-8
12818.0 27
N2645 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
4
IL-8
11805.0 33
N2645 TNF-a 100
ng/mL
4
IL-8
11570.0 25
RA2708 Tofacitinib 0.3
uM
TNF-a 100
ng/mL
4
IL-8
10769.0 24
RA2708 TNF-a 100
ng/mL
4
IL-8
10978.0 33
RA2159 5z-7-oxozeaenol 0.6
uM
4
IL-8
72.0 19
RA2159 IKK16 2.0
uM
4
IL-8
120.0 36
N2645 5z-7-oxozeaenol 0.6
uM
4
IL-8
97.0 32
N2645 IKK16 2.0
uM
4
IL-8
64.0 23
RA2708 5z-7-oxozeaenol 0.6
uM
4
IL-8
286.5 32
RA2708 IKK16 2.0
uM
4
IL-8
629.5 22
RA2159 Tofacitinib 0.3
uM
4
IL-8
158.0 27
RA2159 4
IL-8
172.5 20
N2645 Tofacitinib 0.3
uM
4
IL-8
159.0 29
N2645 4
IL-8
137.5 26
RA2708 Tofacitinib 0.3
uM
4
IL-8
444.5 34
RA2708 4
IL-8
752.0 20