Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 43.0 68
RA2708 PH-797804 0.6
uM
 Poly(I:C) 2
ug/mL
 2
IL-1B
 32.5 76
RA2159 2
IL-1B
 15.0 72
N2645 2
IL-1B
 19.0 76
RA2708 2
IL-1B
 16.0 62
RA2159 JNK-IN-8 3.0
uM
 2
IL-1B
 15.0 86
RA2159 PH-797804 0.6
uM
 2
IL-1B
 18.0 65
N2645 JNK-IN-8 3.0
uM
 2
IL-1B
 14.0 63
N2645 PH-797804 0.6
uM
 2
IL-1B
 16.0 78
RA2708 JNK-IN-8 3.0
uM
 2
IL-1B
 14.0 73
RA2708 PH-797804 0.6
uM
 2
IL-1B
 14.0 76
RA2159 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 16.5 78
RA2159 IKK16 2.0
uM
 2
IL-1B
 15.0 90
N2645 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 16.0 85
N2645 IKK16 2.0
uM
 2
IL-1B
 15.0 80
RA2708 5z-7-oxozeaenol 0.6
uM
 2
IL-1B
 15.0 73
RA2708 IKK16 2.0
uM
 2
IL-1B
 14.0 85
RA2159 Tofacitinib 0.3
uM
 2
IL-1B
 13.0 87
RA2159 2
IL-1B
 18.0 77
N2645 Tofacitinib 0.3
uM
 2
IL-1B
 14.5 90
N2645 2
IL-1B
 15.0 91
RA2708 Tofacitinib 0.3
uM
 2
IL-1B
 16.0 77
RA2708 2
IL-1B
 13.0 54
RA2159 5z-7-oxozeaenol 0.6
uM
 TNF-a 100
ng/mL
 2
IL-1B
 300.0 68
RA2159 IKK16 2.0
uM
 TNF-a 100
ng/mL
 2
IL-1B
 307.0 65