Synovial Fibroblast 3.1: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 1 of 2) - Dataset (ID:20234)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2759 JNK-IN-8 3.0
uM
TNF-a 100
ng/mL
1
IL-2
110.0 43
N2759 PH-797804 0.6
uM
TNF-a 100
ng/mL
1
IL-2
132.5 34
RA1931 JNK-IN-8 3.0
uM
TNF-a 100
ng/mL
1
IL-2
140.0 59
RA1931 PH-797804 0.6
uM
TNF-a 100
ng/mL
1
IL-2
127.0 59
N2586 JNK-IN-8 3.0
uM
TNF-a 100
ng/mL
1
IL-2
137.0 46
N2586 PH-797804 0.6
uM
TNF-a 100
ng/mL
1
IL-2
121.0 42
RA1869 IL-1 alpha 100
ng/mL
1
IL-2
122.0 43
N2759 IL-1 alpha 100
ng/mL
1
IL-2
105.0 63
RA1931 IL-1 alpha 100
ng/mL
1
IL-2
126.0 55
N2586 IL-1 alpha 100
ng/mL
1
IL-2
120.5 60
RA1869 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
IL-2
102.0 61
RA1869 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
IL-2
103.0 59
N2759 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
IL-2
95.5 54
N2759 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
IL-2
97.5 52
RA1931 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
IL-2
116.0 72
RA1931 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
IL-2
106.5 50
N2586 JNK-IN-8 3.0
uM
IL-1 alpha 100
ng/mL
1
IL-2
118.0 55
N2586 PH-797804 0.6
uM
IL-1 alpha 100
ng/mL
1
IL-2
109.0 57
RA1869 Poly(I:C) 2
ug/mL
1
IL-2
69.5 52
N2759 Poly(I:C) 2
ug/mL
1
IL-2
102.0 57
RA1931 Poly(I:C) 2
ug/mL
1
IL-2
89.0 64
N2586 Poly(I:C) 2
ug/mL
1
IL-2
108.0 59
RA1869 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
IL-2
72.0 45
RA1869 PH-797804 0.6
uM
Poly(I:C) 2
ug/mL
1
IL-2
84.5 54
N2759 JNK-IN-8 3.0
uM
Poly(I:C) 2
ug/mL
1
IL-2
81.0 57